blood (6do encyclopedia)



Blood is a vital fluid that circulates throughout the body of animals, including humans. It has many important functions, such as transporting oxygen and nutrients to tissues, removing waste materials, regulating body temperature, and fighting infections. Blood is composed of several different components, including cells, plasma, and various proteins and hormones.

Composition of Blood

The blood of humans and other vertebrates is composed of two main parts: the blood cells, which make up about 45% of the blood volume, and the plasma, which makes up the remaining 55%. Blood cells include red blood cells, white blood cells, and platelets, and each of these cell types plays a different role.

Red Blood Cells

Red blood cells, or erythrocytes, are by far the most numerous type of blood cell, making up about 99% of all blood cells. They are responsible for carrying oxygen from the lungs to the rest of the body and for carrying carbon dioxide back to the lungs to be exhaled. Red blood cells are disc-shaped and have no nucleus or mitochondria, which allows them to carry more oxygen. They are produced in the bone marrow and have a lifespan of about 120 days.

White Blood Cells

White blood cells, or leukocytes, are a diverse group of cells that play a crucial role in the body’s immune system. They are responsible for detecting and fighting off infections and other foreign invaders, such as bacteria, viruses, and parasites. There are several different types of white blood cells, each with a specific function. They are produced in the bone marrow and lymphatic system, and can circulate in the bloodstream or move into the tissues to fight infections.

Platelets

Platelets, also known as thrombocytes, are small, disk-shaped cells that play a crucial role in blood clotting. When a blood vessel is damaged, platelets come into contact with the exposed collagen and other proteins in the damaged area and form a plug, or clot, to stop the bleeding. They are produced in the bone marrow and have a lifespan of about 7-10 days.

Plasma

Plasma is the liquid component of blood, which makes up about 55% of the blood volume. It is composed mainly of water, but also contains various proteins, electrolytes, hormones, and other molecules. Plasma is responsible for carrying the blood cells and the nutrients, hormones, and waste materials they transport. It also plays a role in regulating body temperature and maintaining the body’s fluid and electrolyte balance.

Functions of Blood

Blood has many important functions in the body, including:

Transporting Oxygen and Nutrients

The red blood cells in the blood are responsible for carrying oxygen from the lungs to the rest of the body, and for delivering nutrients, such as glucose and amino acids, to the tissues that need them. The nutrients are absorbed from the digestive system into the bloodstream and transported to the liver, where they are processed and distributed to the rest of the body.

Removing Waste Materials

The blood also plays a crucial role in removing waste materials from the body. The kidneys filter waste products, such as urea and creatinine, from the blood and excrete them in the urine. The liver processes other waste products, such as bilirubin, and excretes them in the bile. The blood carries these waste materials to the organs responsible for excreting them.

Regulating Body Temperature

The blood also helps to regulate the body’s temperature. When the body temperature increases, blood vessels in the skin dilate, allowing more blood to flow to the skin and dissipate heat. When the body temperature decreases, the blood vessels constrict, reducing blood flow to the skin and conserving heat.

Fighting Infections

White blood cells in the blood play a crucial role in the body’s immune system. They detect and fight off infections and other foreign invaders, such as bacteria, viruses, and parasites. They do this by producing antibodies, engulfing and destroying invading organisms, and signaling other cells to come and join in the fight.

Blood Types

Blood types are determined by the presence or absence of certain antigens on the surface of the red blood cells. There are four main blood types: A, B, AB, and O. These blood types are further classified as positive or negative based on the presence or absence of the Rh factor.

Blood type A has the A antigen on the surface of its red blood cells, blood type B has the B antigen, blood type AB has both the A and B antigens, and blood type O has neither. The Rh factor is another antigen that is either present (positive) or absent (negative) on the surface of the red blood cells.

Blood transfusions must be carefully matched to the recipient’s blood type to avoid a potentially fatal immune reaction. A person with blood type A can receive blood types A and O, a person with blood type B can receive blood types B and O, a person with blood type AB can receive all blood types, and a person with blood type O can only receive blood type O. In addition, a person with a negative Rh factor cannot receive blood from a positive Rh donor.

Conclusion

Blood is a vital fluid that circulates throughout the body and performs many important functions. The red blood cells, white blood cells, platelets, and plasma all play different but crucial roles in maintaining the body’s health and functioning. Blood types must be carefully matched to ensure the success of blood transfusions and other medical procedures. The study of blood, known as hematology, is an important field in medicine, biology, and science.


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Court denies Elizabeth Holmes' request to remain free while appealing conviction

Reuters

23-05-17 02:10


Elizabeth Holmes, founder of failed blood-testing startup Theranos, has had her request for bail denied by an appeals court in San Francisco. Holmes, who was sentenced to 11 years and three months in prison after being convicted of defrauding investors, had asked for her sentence to be paused while she appeals her conviction. She rose to fame by claiming Theranos' small machines could run multiple diagnostic tests with just a few drops of blood.

https://www.reuters.com/legal/court-denies-elizabeth-holmes-request-remain-free-while-appealing-conviction-2023-05-17/
Chef whose blood flows backwards says pain ‘cuts like a knife’

The Independent

23-05-17 07:02


A UK single mother suffering from pelvic congestion syndrome has been told by the National Health Service (NHS) that she won't be able to see a blood specialist about her condition until 2024. Lolita Vaciete has been prescribed strong painkillers to manage agonising pain caused by veins in her lower abdomen becoming congested, making everyday tasks highly challenging. She has set up a crowdfunding page to raise the £4,000 it will cost to pay for the treatment she needs privately. Experts have raised concerns that the long waiting times for medical consultations could be contributing to a rise in anxiety levels among UK patients. Data for 2021 reveals that 7.6 million people in England are now on waiting lists for routine hospital procedures, an increase of 4.2%, while 5.3 million have waited longer than 18 weeks for treatment. It is estimated that cases of backlogged treatment lists in parts of the country could take two years or more to resolve.

https://www.independent.co.uk/life-style/health-and-families/pelvic-congestion-syndrome-blood-nhs-b2340316.html
For Robson Green fishing is not escaping life, it’s an immersion in life

The Age

23-05-17 06:02


British TV star Robson Green, host of Fishing Adventures, spoke to The Guardian about his passion for fishing, living in Australia, and his life choices. Green said that being an actor and not having to do something he didn't enjoy for a living had allowed him the freedom to indulge his love of fly-fishing. The actor said that “It is interesting that as I hit the last third of my life, I’m able to choose, and I’m able to do something that is normal, that by design I think we’re meant to do...It doesn’t take a Cambridge professor to realize that we’re made of water, our brains are 73% water, so maybe being next to water and hearing water triggers a mechanism that tells us we’re in the right place." Green, who is also an executive producer and owner of the company that makes his shows, said he was passionate about promoting his home town of Northumberland, pointing out that there had never been a structure there, which meant that people did not had the opportunity to develop and train and move on to the next step.

https://www.theage.com.au/culture/tv-and-radio/for-robson-green-fishing-is-not-escaping-life-it-s-an-immersion-in-life-20230516-p5d8qc.html
Elizabeth Holmes must repay Rupert Murdoch $125m after Theranos fraud

Telegraph

23-05-17 11:29


Convicted fraudster Elizabeth Holmes and her former boyfriend, and co-founder of Theranos, Ramesh "Sunny" Balwani must repay $125m of a court-ordered $452m in restitution for deceiving investors, including Rupert Murdoch. Murdoch invested $100m in the firm in 2014 and 2015 while Theranos's value and profile soared. It later emerged that bosses were secretly sending blood tests to traditional laboratories. Ms Holmes, who was sentenced to 11 years in prison for the scandal, recently told the New York Times she was "playing a character I created" and needed to be taken "seriously".

https://www.telegraph.co.uk/business/2023/05/17/elizabeth-holmes-theranos-fraud-repay-rupert-murdoch-125m/
Theranos founder Elizabeth Holmes loses appeal to remain free, is hit with huge restitution bill

CBC

23-05-17 11:17


Elizabeth Holmes, the former CEO of Theranos, will soon be going to prison to serve 11 years after the Court of Appeals rejected her bid to remain free while she tried to overturn her conviction in a blood-testing hoax that brought her fleeting fame and fortune. U.S. District Judge Edward Davila also ordered Holmes to pay $452m in restitution to the victims of her crimes. Holmes is being held jointly liable for that amount with her former lover and top Theranos lieutenant, Ramesh (Sunny) Balwani, who is already behind bars after being convicted on a broader range of felonies.

https://www.cbc.ca/news/world/theranos-holmes-rulings-1.6845975
Elizabeth Holmes requests new date to report to prison

The Independent

23-05-17 19:45


Elizabeth Holmes, the ex-CEO of blood-testing firm Theranos, has requested to be allowed to spend Memorial Day weekend at home before starting her 11-year prison sentence. She was found guilty of four felony counts of fraud and conspiracy in January 2022, and a US District Court Judge has now ordered her to pay $452m in restitution. Holmes' lawyers have asked for her reporting date to be May 30 to give her two weeks to arrange child care for her two young children. Holmes was previously given a reprieve from her early April reporting date to look after her children.

https://www.independent.co.uk/news/world/americas/elizabeth-holmes-theranos-prison-b2340903.html
Elizabeth Holmes will start 11-year prison sentence on May 30 after losing her bid to remain free

The Globe and Mail

23-05-17 19:37


Elizabeth Holmes, founder of blood-testing company Theranos, will begin serving her sentence on 30 May, following a failed attempt to remain at liberty while she appeals a conviction for fraud and conspiracy in 2022. Holmes, who gained acclaim and funding for her startup claims while still a teenager, was handed an 11-year sentence and ordered to pay $452m in restitution to investors. Holmes’ co-defendant, former romantic and business partner Ramesh “Sunny,” Balwani is currently serving nearly 13 years in prison after being convicted on 12 fraud and conspiracy charges last month.

https://www.theglobeandmail.com/world/article-elizabeth-holmes-will-start-11-year-prison-sentence-on-may-30-after/
Elizabeth Holmes requests May 30 as new date to report to prison after losing her bid to remain free

The Independent

23-05-17 17:59


Disgraced Theranos founder Elizabeth Holmes has asked a federal judge to extend her reporting date to May 30 for beginning her 11-year sentence for defrauding investors in a blood-testing scam. Holmes had recently lost her appeal to remain out of prison while she challenges her conviction on four counts of fraud and conspiracy, to go with a $452m restitution bill. Holmes cited several issues she has to address, including child care for her two young children. Her father is William “Billy” Evans, while Holmes' ex-business and romantic partner, Sunny Balwani, was convicted of crimes related to Theranos.

https://www.independent.co.uk/news/world/americas/elizabeth-holmes-ap-theranos-san-francisco-southern-california-b2340839.html
Theranos fraudster Elizabeth Holmes must repay Rupert Murdoch $188 million

The Sydney Morning Herald

23-05-18 01:00


Theranos founder Elizabeth Holmes and former COO Ramesh Balwani have been ordered to repay $125m to Rupert Murdoch as part of their court-ordered restitution of $452m following their conviction for investor fraud. Murdoch invested $100m in the biotech firm between 2014 and 2015 alongside supporters including Bill Clinton and Henry Kissinger. Lawyers for the pair have suggested they do not have the funds to repay the $425m balance. Holmes has failed in an attempt to remain free while appealing her 11-year prison sentence for the fraud.

https://www.smh.com.au/business/companies/theranos-fraudster-elizabeth-holmes-must-repay-rupert-murdoch-188-million-20230518-p5d9b5.html
McColgan signs up for blood research programme

BBC

23-05-18 05:13


Eilish McColgan, a Commonwealth champion, has signed up with Share, a medical initiative that registers unused blood samples for scientific research into new medicines and treatments. Share holds consented blood samples from routine tests that would otherwise be clinical waste, and scientists can access the stock via an ethically and scientifically vetted bid. Share now has over 300,000 members, with 40,000 people last year taking part in clinical research linked to its database. Actors and other public figures, including Joanna Vanderham and Lorraine Kelly, are also on the list.

https://www.bbc.com/news/uk-scotland-65625798
‘I lost half my family and many friends to a rare illness but it wasn’t too late for me’

Telegraph

23-05-18 14:17


Oscar Lynch tells his story of growing up and living with haemophilia, a disorder where one of the blood-clotting proteins doesn’t work or is missing. He had bleeds into his knees, elbows, ankles and nose that lasted all day and night, and suffered up to 30 haemophilia-related bleeds every year. By the time he was diagnosed at 18 months old, his mother had lost two sons in infancy to haemophilia; brothers he would never meet. At that time, there was no treatment in Ireland for haemophilia. Then came the horror of the contaminated blood scandal when 4,689 people with haemophilia and other bleeding disorders were infected with HIV and hepatitis viruses in the 1970s and 80s through the use of contaminated clotting factors. Lynch was fortunate to escape HIV, but many members of his group were not. In 2019, Lynch volunteered to be part of the clinical trial for the new gene therapy Hemgenix, which works by injecting factor IX, packed inside a virus, into the blood by infusion. Today, he is cured, though nobody knows how long the gene therapy will last.

https://www.telegraph.co.uk/health-fitness/body/i-lost-half-my-family-to-rare-illness-haemophilia/
Research reveals how a single running session can impact appetite

The Independent

23-05-19 12:13


A bout of exercise such as running increases the sensitivity of the brain to cues for anticipating reward and attention, as revealed by a new study. Researchers from the University of Bristol examined whether exercise-induced changes in blood flow in the brain could impact responses to food. As part of the study,23 men underwent fMRI scans before and after a 60-minute running session, with scientists finding the exercise session suppressed hunger levels whilst increasing the reactivity of multiple parts of the brain to food-related cues.

https://www.independent.co.uk/life-style/single-running-session-impact-on-appetite-brain-b2341999.html
Killers of the Flower Moon, Cannes review: Scorsese masterpiece gives DiCaprio his best role yet

Telegraph

23-05-20 20:45


Killers of the Flower Moon, the latest film from Martin Scorsese, premiered yesterday at Cannes. The new movie is being compared favourably to Scorsese’s hit film The Irishman, another sweeping gangster movie that focused on the criminality that pervades the US. Killers of the Flower Moon is a larger-than-life western epic that retells the story of the Osage Indian murders of the 1920s, in which white colonists killed 60 Native Americans in order to secure rights to their oil. The film stars Robert De Niro, Leonardo DiCaprio and Lily Gladstone.

https://www.telegraph.co.uk/films/0/killers-of-the-flower-moon-cannes-review-a-martin-scorsese/